Thomas M Zydowsky Selected Research

Zinc Acetate

12/2017	An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques.
7/2015	MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model.
1/2014	A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explants.
1/2014	A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV.
8/2013	A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo.
11/2012	A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use.
9/2012	An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaques.
1/2011	An antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaques.

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Thomas M Zydowsky Research Topics

Disease

18	Infections 07/2021 - 11/2009
4	Coinfection 01/2017 - 11/2009
4	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2016 - 09/2012
3	Herpes Simplex 01/2018 - 02/2014
3	HIV Infections (HIV Infection) 01/2014 - 01/2011
1	Severe Acute Respiratory Syndrome 05/2022
1	Papillomavirus Infections 01/2018

Drug/Important Bio-Agent (IBA)

13	MIV 150IBA 12/2017 - 11/2009
10	Anti-Infective Agents (Microbicides)IBA 01/2016 - 11/2009
9	CarrageenanIBA 07/2021 - 11/2012
8	Zinc Acetate FDA Link 12/2017 - 01/2011
6	Antiviral Agents (Antivirals)IBA 05/2022 - 11/2014
5	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 01/2017 - 11/2012
3	Contraceptive Agents (Contraceptives)IBA 12/2017 - 09/2015
3	Reverse Transcriptase InhibitorsIBA 02/2014 - 11/2009
2	Griffithsia griffithsin proteinIBA 07/2021 - 01/2018
2	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 07/2015 - 11/2014
2	NucleosidesIBA 09/2012 - 11/2009
1	Levonorgestrel (Plan B)FDA LinkGeneric 12/2017
1	ImmunosorbentsIBA 01/2017
1	EnzymesIBA 01/2017
1	Pharmaceutical PreparationsIBA 01/2014
1	MIV-160IBA 11/2012
1	Vaginal Creams, Foams, and Jellies (Vaginal Tablet)IBA 09/2012
1	HIV Reverse TranscriptaseIBA 09/2012
1	Bulk DrugsIBA 09/2012
1	Local Anti-Infective Agents (Antiseptics)IBA 01/2012
1	GelsIBA 01/2012
1	ZincIBA 01/2011

Therapy/Procedure

1	Contraception (Birth Control) 01/2016